Product Details Sizes:
1 Pound Bulk Powder - or-
As written by Buckmountain:
Glucosamine is not a botanical. It is a natural product and is clearly a medicine of importance in veterinary medicine.
There are a lot of concoctions on the market. There always is someone
who will come up with some farce and put enough hype in the air to sell
it to someone.
- Methylsulfonylmethane (MSM)
- Chondroitin Sulfate
- Glucosamine HCl
- N-acetyl-D-glucosamine (NAG)
- Mixtures of these.
All of these are inferior to unadulterated glucosamine sulfate.
The facts are:
- Chondroitin sulfate is a huge molecule, molecular weight is
approximately 50,000. Its bio-availability is near zero, no more than
13% by the most favorable report.
- Glucosamine bio-availability is 90% to 98%.
- Chondroitin sulfate is expensive.
- Glucosamine HCL is moderately effective but is not as bio-available as glucosamine sulfate and it is more expensive.
- There is no, absolutely no, convincing evidence that MSM is effective.
- It appears that MSM is a catchy name that has gained a following.
- N-acetyl-D-glucosamine (NAG) has no advantage over glucosamine.
- The mixtures of these things are only mixtures of things that are
expensive, don’t work well and if mixed with glucosamine sulfate make it
more expensive and the efficacy of the mixtures is less than that of
glucosamine sulfate alone.
- Glucosamine sulfate is the preferred form and is the least expensive.
Glucosamine is not a complex molecule.
It is manufactured in the body and it stimulates the synthesis of
glycoaminoglycans (GAG). It also potentiates the incorporation of sulfur
into cartilage. This is one of the reasons glucosamine sulfate is the
preferred form of glucosamine.
There are over 300 studies on glucosamine sulfate and few on MSM, NAG
and GHCl. Those that do exist are negative or published, largely
unrefereed by those wishing to sell their products.
Some authors are so down on everything but glucosamine sulfate that
they deny the GHCl has any merit whatsoever. From the literature and
personal experience with horses and dogs, it is believed that
glucosamine sulfate is clearly the star and other concoctions are just
that — concoctions. There is however merit to glucosamine-HCl.
Glucosamine sulfate is an anti-inflammatory alternative to NSAIDS,
aspirin, licorice, etc. Licorice used with glucosamine sulfate for
arthritis is effective. Glucosamine sulfate works – 5 to 10 days and
results are apparent.